Can we use our custom master page with the application pages in SharePoint 2010

Can we use our custom master page with the application pages in SharePoint 2010

With 2010, you can now set whether the pages under _Layouts use the same Master Page as the rest of your site. You can enable or disable this functionality through the web application settings in Central Administration. This however, is not applicable to your custom application pages. If you want your custom applictaion page to inherit the site master page you must derive it from Microsoft.SharePoint.WebControls.LayoutsPageBase class.